Subclinical late cardiac toxicity in childhood cancer survivors
نویسندگان
چکیده
منابع مشابه
Subclinical Hypothyroidism in Childhood Cancer Survivors
PURPOSE In childhood cancer survivors, the most common late effect is thyroid dysfunction, most notably subclinical hypothyroidism (SCH). Our study evaluated the risk factors for persistent SCH in survivors. MATERIALS AND METHODS Survivors (n=423) were defined as patients who survived at least 2 years after cancer treatment completion. Thyroid function was assessed at this time and several ye...
متن کاملLate effects in survivors of childhood cancer.
Case Presentation A 19-year-old male was treated for cerebellar medulloblastoma at 3 years of age. Therapy included total resection followed by craniospinal radiation in a dose of 3,600 cGy, with a boost to 5,040 cGy to the tumor bed, as well as chemotherapy with vincristine, cyclophosphamide, and cisplatin. School was a struggle, and he was held back in the 8th grade. One physician suggested m...
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BACKGROUND Treatment with bleomycin-etoposide-cisplatin (BEP) impairs renal function and increases the risk of late cardiovascular disease (CVD) and death. We investigated the influence of BEP on glomerular filtration rate (GFR) and assessed the importance of GFR changes on CVD and death in a large cohort of germ-cell cancer survivors. PATIENTS AND METHODS BEP-treated patients (N = 1206) were...
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Neurocognitive late effects are common sequelae of cancer in children, especially in those who have undergone treatment for brain tumors or in those receiving prophylactic cranial radiation therapy to treat leukemia. Neurocognitive morbidity in attention, executive functioning, processing speed, working memory, and memory frequently occurs and contributes to declines in intellectual and academi...
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Childhood cancer treatments can cause female reproductive late effects. Radiation to the hypothalamic-pituitary-ovarian axis is associated with altered menarche, miscarriage, and implantation failure. Patients who receive chemotherapy and/or ovarian radiation are at risk of premature ovarian failure; the risk increases with increasing radiation dose, alkylating agent score, combination therapy,...
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ژورنال
عنوان ژورنال: Cancer
سال: 2008
ISSN: 0008-543X,1097-0142
DOI: 10.1002/cncr.23378